$1,000,000 – Noah Wilson’s Fund for Pediatric Cancer Research (Noah’s Fund) – 2018

First Project for Noah’s Fund – $200,000 – April 2018

Dr. Erin Guest is a pediatric oncologist at Children’s Mercy Kansas City and an Associate Professor of Pediatrics, University of Missouri-Kansas City.  She was Noah’s Oncologist.  Her research focuses on improving survival for infants with acute lymphoblastic leukemia (ALL).  Dr. Guest is leading a research team in the Center for Pediatric Genomic Medicine at Children’s Mercy.  The team is looking for markers in the DNA and patterns of gene expression that help explain why infant ALL is so difficult to cure.  Less than half of infants with ALL survive and clinical trials that have added more chemotherapy have resulted in more side effects, but have not improved the cure rate.  Dr. Guest and her team are taking the information they learn from the genomes of leukemia samples from infants to test new treatments in the lab.  The funds from Noah’s Bandage Project are funding this testing, as well as genomic sequencing studies both before and after the leukemia cells are treated.  The hope is that the research will identify promising treatments that can then be tested in clinical trials.